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The NIH AIDS Reagent Program has been transitioned to the NIH HIV Reagent Program which is managed by American Type Culture Collection (ATCC). We want to ensure your continued use of the materials within the NIH HIV Reagent Program with minimal impact to you. The NIH HIV Reagent Program materials are provided at no cost to registered researchers (shipping charges apply).
Additional SIV and SHIV stocks produced for NIAID are available through Quality Biological. Click here for a list of items.
ARP-12425 is a 123-peptide pool comprising the Human Immunodeficiency Virus Type 1 (HIV-1) subtype B consensus Gag region. Most of the peptides are produced as 15-mers with 11 amino acid overlaps between sequential peptides. These peptides are used for Gag-specific T cell induction. The individual peptide is available as ARP-8117. Click Here for more information on ARP-12425.
Image credit: (PBD DOI:7ASL)
One of the most requested reagents in the HRP catalog is the recombinant Trans-Activator of Transcription (TAT) regulatory protein, ARP-2222. This biologically active, full-length recombinant protein, derived from Human Immunodeficiency Virus Type 1, strain IIIB, is produced in E. coli and purified by heparin-sepharose affinity chromatography. ARP-2222 is ideal for in vitro transcription assays and in vivo protein-binding and functional assays. Click Here for more information on ARP-2222.
Image credit: (PDB ID/3MIA)
ARP-12028, Human Immunodeficiency Virus-Type 1 (HIV-1) IIIB p24 Protein, Recombinant from Baculovirus, is a key element to construct a conical-shaped viral core. The appropriate form of the core structure is essential for virus infection. It was once believed that core uncoating occurred in the cytoplasm. However, recent findings show that intact core has been delivered to the integration site in the nucleus. A related item is ARP-13126.
Image credit: (Molpgraphfan/CC-BY-SA-4.0)
ARP-95, HIV-1 LAV-Infected 8E5 cells, is a cell line known to contain a single integrated copy of HIV provirus per cell, which directs synthesis of defective virus particles. This cell line can be used for HIV genome quantification. Click here for more information on ARP-95.
Image credit: (NIAID/CC BY 2.0)
For information and forms regarding registration with the NIH HIV Reagent Program, click here.
After your registration application has been approved by NIAID and ATCC, you will receive a login name and password. After logging in, find the reagent you need using the search function. Select the items from the search results to see the product detail pages. After you read the product detail page description, click the "Add to cart" button to place the item into your shopping cart. The NIH HIV Reagent Program materials are provided at no cost to registered researchers (shipping charges apply). For additional information, click here.
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The NIH HIV Reagent Program acquires, authenticates, produces and distributes a variety of materials within several biosafety levels and classifications. We understand that some researchers may only choose to order non-infectious research grade reagents through the NIH HIV Reagent Program.
The Knowledge Base is an informational database assembled by our Support Specialists and Scientific Staff which provides additional knowledge about the NIH HIV Reagent Program and reagents through questions and answers.
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